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. Author manuscript; available in PMC: 2012 Oct 22.
Published in final edited form as: Clin Trials. 2008;5(2):121–130. doi: 10.1177/1740774508089278

Table 3.

23 factorial design (interventional components fully randomized)

Factor
combination
Manual dexterity
impairment
Chair lift
impairment
Depression Number of
data points
Estimated effect
contribution [1,2]
1 0 0 0 40 All
2 0 0 1 40 All
3 0 1 0 40 All
4 0 1 1 40 All
5 1 0 0 40 All
6 1 0 1 40 All
7 1 1 0 40 All
8 1 1 1 40 All
Total data points = 320

Estimated
bootstrap
effect (95% CI)3
Hand skill impairment
0.28
(−0.05, 0.60)
Chair lift impairment
0.38
(0.05, 0.75)
Depression
0.40
(0.05, 0.79)
Net Intervention
0.23
(−0.43, 1.08)
1

Estimates from Poisson regression on number of falls in 3 years with fixed offset.

2

All includes effects for net intervention and individual components for hand, chair, and depression.

3

Bootstrap estimates based on 1000 re-samplings of non-missing values of original data set.