Table 4. Grade 1-4 Non-Hematological Toxicity ( ≥10% Frequency).
| N=47 | Grade | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | % Pts | |
| Constitutional | |||||
| Anorexia | 7 | 5 | 3 | 0 | 32% |
| Weight Loss | 7 | 5 | 2 | 0 | 30% |
| Fatigue | 13 | 10 | 7 | 0 | 64% |
| Dehydration | 0 | 3 | 3 | 0 | 13% |
| Gastrointestinal | |||||
| Nausea | 10 | 4 | 2 | 0 | 34% |
| Vomiting | 5 | 3 | 1 | 0 | 19% |
| Diarrhea | 14 | 12 | 4 | 0 | 64% |
| Constipation | 4 | 1 | 1 | 0 | 13% |
| Heartburn | 3 | 2 | 0 | 0 | 11% |
| ENT | |||||
| Dry mouth | 4 | 1 | 0 | 0 | 11% |
| Voice Changes | 14 | 3 | 0 | 0 | 36% |
| Cardiac | |||||
| Hypertension | 5 | 14 | 14 | 1 | 70% |
| Respiratory | |||||
| Cough | 5 | 1 | 0 | 0 | 13% |
| Renal | |||||
| Proteinuria | 8 | 4 | 2 | 0 | 30% |
| Musculoskeletal | |||||
| Muscle pain | 3 | 1 | 0 | 0 | 9% |
| Neurologic | |||||
| Headache | 4 | 1 | 1 | 0 | 13% |
| Sensory neuropathy | 3 | 0 | 1 | 0 | 9% |
| Endocrine | |||||
| Hypothyroidism | 2 | 4 | 0 | 0 | 13% |