Table 1.
Incidence of medullary and invasive ductal carcinomas among the 13 International Breast Cancer Study Group trials analyzed
| All patients (full cohort) |
Patients with grade 3 and estrogen receptor-negative tumors (restricted cohort) |
|||
|---|---|---|---|---|
| Medullary | Ductal | Medullary | Ductal | |
| Total patients (% total trial accrual) | 127 (1) | 8096 (65) | 47 (0.4) | 1407 (11) |
| Trials with central pathology review | ||||
| I | 13 | 306 | 5 | 34 |
| II | 4 | 216 | 0 | 29 |
| III | 19 | 289 | 3 | 24 |
| IV | 8 | 206 | 3 | 10 |
| V | 18 | 1701 | 11 | 350 |
| VIII | 8 | 693 | 6 | 135 |
| IX | 5 | 1065 | 5 | 178 |
| 11 | 1 | 98 | 0 | 1 |
| 12 | 0 | 277 | 0 | 2 |
| 13 | 0 | 799 | 0 | 247 |
| 14 | 3 | 622 | 3 | 198 |
| Trials with local pathology review | ||||
| VI | 26 | 991 | 7 | 120 |
| VII | 22 | 833 | 4 | 79 |