Table 2.
Distribution of 5048 cases of pancreatic cancer and 10 947 controls, pooled odds ratios (ORs) and 95% confidence intervals (CIs) for history of pancreatitis and risk of pancreatic cancer, International Pancreatic Cancer Case-Control Consortium (PanC4)
| Cases |
Controls |
ORa (95% CI) | |||
|---|---|---|---|---|---|
| N | % | N | % | ||
| History of pancreatitis | |||||
| No | 4674 | 92.6 | 10 703 | 97.8 | 1b |
| Yes | 313 | 6.2 | 112 | 1.0 | 5.57 (4.39–7.07) |
| Missing | 61 | 1.2 | 132 | 1.2 | |
| Years between diagnosis of pancreatitis and diagnosis of pancreatic cancer/interviewc | |||||
| ≤1 | 156 | 49.8 | 14 | 12.5 | 21.35 (12.03–37.86) |
| >1 to 2 | 27 | 8.6 | 11 | 9.8 | 4.08 (1.90–8.78) |
| >2 to 5 | 31 | 9.9 | 19 | 17.0 | 2.82 (1.47–5.39) |
| >5 to 10 | 30 | 9.6 | 17 | 15.2 | 3.33 (1.74–6.37) |
| >10 to 25 | 25 | 8.0 | 28 | 25.0 | 1.90 (1.06–3.39) |
| >25 | 20 | 6.4 | 15 | 13.4 | 3.45 (1.67–7.13) |
| Missing | 24 | 7.7 | 8 | 7.1 | |
| P value for trendc | <0.0001 | ||||
aPooled ORs were estimated using logistic regression models adjusting for study, age, sex, race/ethnicity, education, body mass index, tobacco smoking, alcohol intake and history of diabetes.
bReference category.
cAmong participants with pancreatitis.