Table 3.
Association of asthma-related traits with ancestry in the SAGE subjects.
Ancestry * | ||||
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Trait | ADMIXMAP | Structure2.1 | ||
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Coefficients ** | P value | Coefficients | P value | |
Disease status | −.303 | 0.818 | −.160 | 0.856 |
Asthma severity | −.671 | 0.750 | −.515 | 0.716 |
Pre-FEV1 | −39.322 | 0.008 | −25.980 | 0.009 |
Pre-FEV1/FVC | −.817 | 0.929 | −.041 | 0.995 |
Pre-FEF25-75 | −18.596 | 0.442 | −11.935 | 0.461 |
Δ FEV1 | .472 | 0.226 | .298 | 0.254 |
Δ FEV1/FVC | −.278 | 0.521 | −.175 | 0.542 |
Δ FEF25-75 | .301 | 0.455 | .196 | 0.466 |
IgE | .196 | 0.753 | .131 | 0.752 |
NOTE:
Estimates of ancestry, individual ancestral estimates (IAEs), are obtained either by ADMIXMAP or Structure2.1.
Covariates included in the analyses are age, gender, SES, asthma duration, regular use of asthma medication and BMI.