Table 4.
Association of asthma-related traits with 30 ancestry informative markers in the SAGE subjects.
Count of positives ‡ (P value < 0.05) * | |||
---|---|---|---|
|
|||
Trait | No adjustment | w/covariates adjustment, but w/o IAEs adjustment ** |
w/covariates and IAEs adjustment |
Disease status | 0 | 0 | 0 |
Asthma severity | 1 | 0 | 1 |
Pre-FEV1 | 3 | 3 | 2 |
Pre-FEV1/FVC | 1 | 1 | 1 |
Pre- FEF25-75 | 1 | 2 | 2 |
Δ FEV1 | 2 | 2 | 2 |
Δ FEV1/FVC | 1 | 0 | 0 |
Δ FEF25-75 | 0 | 0 | 0 |
IgE | 2 | 2 | 2 |
NOTE:
Under 5% type I error rate (P = 0.05), counts of expected false positives are 1.5 markers.
Analyses were carried out by using multiple regression analysis.
Covariates included in the analyses are age, gender, SES, asthma duration, regular use of asthma medication and BMI.