Table 3.
Distribution of 111In-DTPA-Ac-TZ14011. Mice were killed 24 hours after injection of 111In-DTPA-Ac-TZ14011. Tissues were excised and radioactivity in the tissues was determined using a gamma counter. %ID/g was calculated using the following formula: ((MBq measured in tissue/injected dose) *100%)/weight tissue.
| Tissue | %ID/g |
|---|---|
| Blood | 0.02 ± 0.00 |
| Brain | 0.00 ± 0.00 |
| Lungs | 0.19 ± 0.01 |
| Heart | 0.08 ± 0.01 |
| Liver | 5.53 ± 0.51 |
| Kidneys | 24.82 ± 0.94 |
| Spleen | 1.03 ± 0.11 |
| Stomach | 0.08 ± 0.01 |
| Intestines | 0.16 ± 0.02 |
| Muscle | 0.03 ± 0.01 |
| Mammary fatpad | 0.05 ± 0.02 |
| Axillary lymph nodes | 1.33 ± 0.81 |