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. 2012 Apr 20;1(1):12–19.

Figure 1.

Figure 1

Pregnancy induces remission of inflammatory arthritis in SKG mice. A, Single representative cohort of SKG mice treated with zymosan and then mated to compare arthritis kinetics in pregnant (n=1) and non-pregnant (n=2) mice through pregnancy and post-delivery. B, Gross morphology of wrist joints of SKG mice treated with zymosan from both non-pregnant (a) and pregnant (c) mice on gestational day E14.5. Representative histology of digit joints stained with toluidine blue from SKG+Z (b) and SKG+Z+P (d) mice at day E14.5. White asterisks identify synovial lymphocytic infiltrate and pannus formation (c). C, Distribution of percentage of arthritis scores for non-pregnant (n=23) and pregnant (n=14) zymosan-treated SKG mice on gestational day E14.5. D, Change in arthritis score for non-pregnant (n=23) and pregnant (n=14) zymosan-treated SKG mice from gestational day E0.5 to E14.5.