Table 1.
P4 | P1a | |
---|---|---|
Monocyte/PMN subset marker/Migration |
|
|
Ly6C |
+ |
-/+ |
Ly6G |
++ |
- |
CXCR2 |
++ |
- |
CCR3 |
+ |
- |
Siglec-F |
- |
-/+ |
F4/80 |
- |
++ |
CXCR4 |
- |
- |
CD62L |
- |
- |
CD49d |
++ |
++ |
Adhesion/Activation Molecules |
|
++ |
CD44 |
++ |
++ |
CD43 |
++ |
- |
CD103 |
- |
- |
CD138 |
++ |
++ |
CD54 (ICAM-1) |
++ |
++ |
Antigen presentation |
|
- |
MHC I |
++ |
- |
MHC II |
- |
- |
CD86 (B7-2) |
+ |
+ |
CD11c |
- |
- |
Differentiation |
|
- |
CD119 (IFNGR1) |
++ |
- |
CD124 (IL-4Ra) |
++ |
+ |
CD115 (CSFR1) |
- |
- |
CD309 (VEGFR2) |
+ |
+ |
Potential T-cell suppressive marker |
|
|
B7H1 (PD-L1) |
+ |
+ |
B7DC (PD-L2) |
- |
- |
FASL |
+ |
- |
Pattern recognition receptor |
|
- |
CD14 |
- |
- |
TLR2 | + | + + |
Expression of the indicated cell surface markers was evaluated on gated SSChi CD11bhi Gr-1dim F4/80+ P1a and Gr-1hi CD11bhi F4/80- (P4) cells. “-” indicates no expression and “+”, “++”, increasing amount of expression to isotype-matched controls.