Table 4.
Factors associated with the presence of day-3 parasitaemia after treatment with mefloquine and artesunate 12 mg/kg*
|
Variable |
Level |
Day-3 parasitaemia (n) |
Univariate |
Multivariable |
|||
|---|---|---|---|---|---|---|---|
| yes | no | OR | 95% CI | OR | 95% CI | ||
| Region |
East |
27 |
365 |
2.79 |
(1.59, 4.90) |
4.69 |
(2.48, 8.88) |
| |
West |
24 |
905 |
1.† |
|
1. |
|
| Year |
1997 |
0 |
89 |
1.12‡ |
(0.98, 1.27) |
1.29 |
(1.12, 1.49) |
| |
1998 |
0 |
37 |
|
|
|
|
| |
2002 |
5 |
140 |
|
|
|
|
| |
2003 |
9 |
180 |
|
|
|
|
| |
2004 |
10 |
97 |
|
|
|
|
| |
2005 |
9 |
272 |
|
|
|
|
| |
2006 |
9 |
307 |
|
|
|
|
| |
2007 |
9 |
148 |
|
|
|
|
| Age |
≤18 |
4 |
229 |
1. |
|
1. |
|
| |
19-29 |
31 |
635 |
2.79 |
(0.98, 8.00) |
2.43 |
(0.84, 7.02) |
| |
≥30 |
14 |
348 |
2.30 |
(0.75, 7.08) |
1.60 |
(0.50, 5.14) |
| Parasitaemia |
<10000 |
21 |
641 |
1. |
|
1. |
|
| (parasites/μl) |
10000-50000 |
26 |
522 |
1.52 |
(0.85, 2.73) |
1.53 |
(0.84, 2.79) |
| >50000 | 4 | 107 | 1.14 | (0.38, 3.39) | 1.04 | (1.34, 3.19) | |
Abbreviations: OR, odds ratio; CI, confidence interval.
*Results from both univariate and multivariable logistic regression are presented. Multiple imputation was used for age in the multivariable but not the univariate analyses.
†reference level.
‡Year was coded as a continuous variable so the OR represents the comparison per one year increase in time.