Table 5.
Uncorrected | Alker 2007 | Hutagalung 2005 | Rogers 2009 | |
---|---|---|---|---|
Sensitivity |
25.9 |
22.6 |
15.1 |
15.4 |
Specificity |
88.5 |
95.0 |
94.6 |
95.1 |
PPV |
13.5 |
27.8 |
24.2 |
34.3 |
NPV | 94.6 | 93.4 | 90.6 | 87.0 |
Abbreviations: PPV positive predictive value, NPV negative predictive value.
*The uncorrected estimates are from this study. The relationship between day-28 PCR-uncorrected treatment failure and 42-day PCR-corrected treatment failure from three different studies was used to calculate the sensitivity, specificity, PPV, and NPV of day-2 parasitaemia as an indicator of 42-day PCR-corrected treatment failure.