Table 4.
Association between combined score of one-carbon metabolism related nutrients intake and disease progression in breast cancer patients stratified by selected characteristics
| Combined score | No. of total | No. of events | HR (95%CI)a | |
|---|---|---|---|---|
| Hormone statusb |
|
|
|
|
| ER + and/or PR+ |
Low (0) |
211 |
29 |
1.00 |
| |
Medium (1–2) |
202 |
16 |
0.54 (0.29-1.02) |
| |
High (3) |
285 |
29 |
0.72 (0.37-1.43) |
| |
Ptrend |
|
|
0.29 |
| ER–/PR– |
Low (0) |
87 |
15 |
1.00 |
| |
Medium (1–2) |
82 |
19 |
2.02 (0.96-4.27) |
| |
High (3) |
95 |
30 |
3.84 (1.70-8.71) |
| Ptrend | 0.001 |
Abbreviation: ER, estrogen receptor; PR, progesterone receptor.
a Adjusted for age, education, recruited site, TNM stage, hormone status, nuclear grade and total calorie.
bP for interaction = 0.018.