Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of HDL/apoA-I on autophagy in preadipocyte. HDL/apoA-I activated PI3K-Akt signaling pathway through SR-BI dependent mechanism and/or S1P of HDL binding to S1P receptor. Activated Akt positively regulated the activity of mTORC1 with consequent autophagy inhibition. apoA-I, apolipoprotein A-I; HDL, high density lipoprotein; PI3K, phosphatidylinositol 3-kinase; S1P, sphingosine-1-phosphate.
