Table 3.
Association of different Hsp70 expression patterns and clinicopathological characteristics in NPC patients
|
Characteristics |
Hsp70 membranal and cytoplasmic staining |
P value |
Hsp70 nuclear staining |
P value |
||
|---|---|---|---|---|---|---|
| low expression (n = 281) | high expression (n = 226) | low expression (n = 370) | high expression (n = 137) | |||
|
Age, years |
|
|
0.751 |
|
|
0.857 |
| <46 |
131 |
116 |
|
176 |
71 |
|
| > = 46 |
145 |
115 |
|
188 |
72 |
|
|
Sex |
|
|
0.828 |
|
|
0.715 |
| Male |
209 |
170 |
|
275 |
104 |
|
| Female |
72 |
56 |
|
94 |
34 |
|
|
Tumor stage |
|
|
0.001 |
|
|
0.401 |
| T1 + T2 |
96 |
109 |
|
153 |
51 |
|
| T3 + T4 |
186 |
116 |
|
217 |
86 |
|
|
Lymphoid Nodal(N) state |
|
|
0.061 |
|
|
0.468 |
| N0 |
64 |
69 |
|
94 |
40 |
|
| N1-3 |
217 |
157 |
|
276 |
97 |
|
|
Recurrence or metastasis |
|
|
0.002 |
|
|
0.016 |
| Yes |
126 |
71 |
|
132 |
65 |
|
| No |
155 |
155 |
|
238 |
72 |
|
|
TNM clinical stage |
|
|
0.005 |
|
|
0.900 |
| I + II |
63 |
76 |
|
102 |
37 |
|
| III + IV | 218 | 150 | 268 | 100 | ||
Hsp70, heat shock protein 70.