Table 3. Distributions of genotypes of inflammasome genes and their associations with risk of CWP.
| Variables | CWP cases | Controls | P a | OR (95% CI) | OR (95% CI)b | ||
| N | % | N | % | ||||
| NLRP3(rs1539019) | n = 693 | n = 690 | |||||
| GG | 186 | 26.8 | 217 | 31.5 | 0.028 | 1.00 | 1.00 |
| GT | 345 | 49.8 | 348 | 50.4 | 1.16 (0.90–1.48) | 1.16 (0.91–1.48) | |
| TT | 162 | 23.4 | 125 | 18.1 | 1.51 (1.12–2.05) | 1.53 (1.12–2.07) | |
| G allele | 717 | 51.7 | 782 | 56.7 | 0.009 | 1.00 | |
| T allele | 669 | 48.3 | 598 | 43.3 | 1.22 (1.05–1.42) | ||
a
Two-sided χ2 test.
b
Adjusted for age, exposure years, and pack-years of smoking in logistic regression model.