Figure 3. Trif is required for foam cell formation.
BMDM from B6, MyD88−/− or Trif−/− mice were treated and quantitated as described in Fig 1 with no lipid source (A) or liposomes composed of either 0% (B) or 50% (C) cholesterol. An average of 1300 cells from 9 independent experiments were counted for B6 and Trif−/− and an average of 1000 cells from 6 independent experiments were counted for MyD88−/−. * indicates p<0.05, *** p<0.001 from B6.