Table 1.

Phenotypic distribution of bone marrow B cells

Sample	Control†, %	DSS-treated mice, %
Pre Pro-B cells‡	3.9 ± 0.3	2.6 ± 0.9**
Late Pro-B cells	10.7 ± 1.2	23.6 ± 3.0***
Large Pre-B cells	11.0 ± 1.3	3.2 ± 1.6***
Small Pre-B cells	50.0 ± 2.2	37.9 ± 6.0**
Immature B cells	12.0 ± 1.0	10.2 ± 0.9**
Mature B cells	4.3 ± 0.5	6.2 ± 3.3

**P < 0.01

***P < 0.001.

^†Data shown is percent of B220⁺ population (26.2 ± 2.3% of nucleated marrow for controls, 8.0 ± 1.6% for DSS-treated mice).

^‡Pre Pro-B cells (B220⁺ Gr-1⁻ CD43^hi IgM⁻ CD19⁻); Late Pro-B cells (B220⁺ Gr-1⁻ CD43^hi IgM⁻ CD19⁺); Large Pre-B cells (B220⁺ Gr-1⁻ CD43^−/low IgM⁻ FSC^high); Small Pre-B cells (B220⁺ Gr-1⁻ CD43^−/low IgM⁻ FSC^low); Immature B cells (B220⁺ Gr-1⁻ CD43^−/low IgM⁺ IgD⁻); Mature B cells (B220⁺ Gr-1⁻ CD43^−/low IgM⁺ IgD⁺).