Table 2.
PGE2 levels in BALF after OVA+2fAP-induced airway inflammation model
| Mouse strain | Sensitization | Challenge | PGE2 levels, pg/mL |
| WT | None | Saline | 1.4 ± 0.23 |
| WT | OVA+Al(OH3) | OVA+CP | 2.2 ± 0.18 |
| WT | OVA+Al(OH3) | OVA+2fAP | *3.4 ± 0.15 |
| βarr2−/− | None | Saline | 1.8 ± 0.31 |
| βarr2−/− | OVA+Al(OH3) | OVA+CP | 2.2 ± 0.29 |
| βarr2−/− | OVA+Al(OH3) | OVA+2fAP | **3.2 ± 0.06 |
BALF supernatants were assayed for prostaglandin (PGE2) levels using PGE2 Express AChE tracer ELISA. Values are mean ± SEM (n = 8). Statistically significant differences from control group are indicated as follows: *P = 0.0003, **P = 0.0001 (n = 15 for saline, n = 20 for OVA+CP and OVA+2fAP).