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. 2012 Sep 26;109(41):16606–16611. doi: 10.1073/pnas.1210129109

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Fig. 1. — IL-2 and IL-17A mRNA expression and promoter methylation in CD4⁺ T cells. (A) IL-2 mRNA expression of naive, central memory (CM) and effector memory (EM) CD4⁺ T cells in response to stimulation with anti-CD3 and anti-CD28 antibodies (mean ± SD). (B) CpG-DNA methylation of the IL2 promoter in CD4⁺ T cells. Methylation index (MI) as assessed relative to methylated (100%) and unmethylated (0%) control DNA are shown (mean ± SD). (C) IL-17A mRNA expression of naive, CM and EM CD4⁺ T cells in response to stimulation with anti-CD3 and anti-CD28. (D) CpG-DNA methylation of the IL17A promoter in CD4⁺ T cells (mean ± SD).