Fig. 3.

Computed vs. observed spatial expression in real time. The genes are indicated at the top and the comparison symbolism is as in Fig. 2; i.e., plain filled colored or gray squares indicate exact congruence between computed and predicted expression. The four embryonic spatial domains (A–D) are separately portrayed, each against 1- to 30-h time scales. Open rectangles indicate discrepancies <3 h; as described in the text, as the observations have only 3-h resolution, these discrepancies may not be real. Discrepancies >3 h are indicated by black solid rectangles. The green striped bars indicate maternal mRNAs that are not part of the zygotic GRN model and therefore not computationally predicted. Some of these maternally supplied factors provide initial inputs to the computation. The three places where the whole column is striped (delta, foxa, and wnt8) indicate phases of expression or nonexpression known to occur, but not explained, and set manually in the computation.