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Mean Arterial Pressure in EP1+/+ and EP1−/− mice. Intracarotid blood pressure was measured in EP1+/+ and EP1−/− mice two days post-Ang II administration under ketamine and inactin anesthesia. MAP was elevated in both groups compared to baseline (EP1+/+ ##P = 0.0004, EP1−/− #P = 0.0423) but was significantly lower in EP1−/− compared to EP1+/+ two days post-Ang II (*P = 0.0295).
