Table 2.

Association Analyses of T2DM Susceptibility Genes With NODAT

			Frequency of High-Risk Allele
Gene	SNP	Alleles*	Cases (%)	Controls (%)	Odds Ratio (95% CI)†	Odds Ratio (95% CI)‡
TCF7L2	rs12255372	G/T	20.4	18.8	1.10 (0.48–2.52)	0.98 (0.41–2.30)
TCF7L2	rs7901695	T/C	27.3	24.6	1.12 (0.54–2.32)	0.98 (0.45–2.14)
KCNJ11	rs5219	C/T	36.3	35.5	1.03 (0.52–2.01)	0.93 (0.45–1.94)
KCNJ11	rs5215	C/T	63.6	62.3	1.05 (0.54–2.02)	1.15 (0.56–2.36)
PPARG	rs1801282	G/C	86.3	86.9	0.96 (0.39–2.34)	1.02 (0.36–2.85)
SLC30A8	rs13266634	T/C	77.2	73.9	1.19 (0.54–2.57)	1.17 (0.48–2.84)
CDKN2A/CDKN2B	rs10811661	C/T	79.5	80.4	0.95 (0.435–2.13)	1.42 (0.55–3.58)
CDKN2A/CDKN2B	rs564398	G/A	63.6	66	0.91 (0.45–1.81)	1.20 (0.54–2.66)
IGF2BP2	rs4402960	G/T	31.8	24.6	1.44 (0.67–3.07)	1.16 (0.51–2.63)
IGF2BP2	rs1470579	A/C	36.3	29.7	1.31 (0.66–2.59)	1.21 (0.56–2.60)
CDKAL1	rs10946398	A/C	34.1	27.5	1.38 (0.65–2.91)	1.84 (0.79–4.28)
CDKAL1	rs7756992	A/G	31.8	26.1	1.39 (0.61–3.17)	2.06 (0.81–5.28)
CDKAL1	rs7754840	G/C	34.1	30.4	1.19 (0.57–2.50)	1.69 (0.72–3.95)
HHEX	rs1111857	A/G	63.6	60.8	1.11 (0.57–2.16)	1.33 (0.66–2.69)
HHEX	rs5015480	T/C	61.4	57.2	1.14 (0.61–2.15)	1.32 (0.67–2.58)
Multiallelic risk					1.10 (0.89–1.35)	1.06 (0.82–1.38)

^*Underlined and bold alleles are diabetes-associated alleles as described in prior studies.

^†Odds ratio (unadjusted) per copy of the risk allele.

^‡Odds ratio: adjusted (age, gender, race) per copy of the risk allele.