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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Radiat Res. 2012 Sep 5;178(4):321–327. doi: 10.1667/rr2800.1

TABLE 1.

Tumor Size and Growth as a Function of Postirradiation Time and Dose

Radiation dose 3 month [mm3]† 6 month [mm3]† 9 month [mm3]† Growth rate* [ln(mm3)/month]† Growth curve R2 Volume doubling time (months)
Sham (n = 14, 5)# 0.18 (0.05) 0.80 (0.16) 3.29 (1.07) 0.46 (0.04) 0.97 1.5
10 mGy × 4 (n = 8, 4)# 0.31 (0.07) 1.74 (0.57) 3.88 (1.15) 0.39 (0.07) 0.84 1.8
30 mGy × 4 (n = 14, 4)# 0.36 (0.21) 1.01 (0.37) 4.03 (1.83) 0.41 (0.05) 0.97 1.7
50 mGy × 4 (n = 14, 4)# 0.30 (0.10) 1.29 (0.44) 2.70 (0.70) 0.41 (0.05) 0.93 1.7
#

Number of tumors, number of mice.

†

Values in parentheses are standard errors of the means.

*

The tumor growth rate was determined from a linear regression analysis of the loge transform of the individual tumor sizes as a function of time after the last fraction of irradiation.