Table 1.
List of S. pombe SIN proteins and their homologs in S. cerevisiae and H. sapiens.
| Core SIN components | |||
|---|---|---|---|
| S. pombe | S. cerevisiae | H. sapiens | gene product |
| Sid4 | Cnm67p? | Kendrin? | Scaffold |
| Cdc11 | Nud1p | Centriolin | Scaffold |
| Spg1 | Tem1p | ? | GTPase |
| Cdc7 | Cdc15p | MST2? | Ste20 family protein kinase |
| Sid1 | ? | MST2? | PAK-related protein kinase |
| Cdc14 | ? | ? | Sid1co-factor |
| Sid2 | Dbf2p | LATS1 | NDR family protein kinase |
| Mob1 | Mob1p | MOB1A | Sid2 co-factor |
| Byr4 | Bfa1p | ? | GAP scaffold |
| Cdc16 | Bub2p | GAPCENA | GAP |
| Etd1 | Lte1p | ? | GEF-like protein |
| SIN regulators | |||
| S. pombe | S. cerevisiae | H. sapiens | gene product |
| Plo1 | Cdc5p | PLK1 | Polo-like protein kinase |
| Dma1 | Dma1p/Dma2p | CHFR/RNF8 | E3 ubiquitin ligase |
| Clp1 | Cdc14p | CDC14 | protein phosphatase |
| Cdc2 | Cdc28p | CDK | protein kinase |
| Zfs1 | Tis11p/cth1p | ? | Zn finger protein |
| Par1 | Rts1p | ? | PP2A B′ subunit |
| Csc1 | Far10p | SLMAP | PP2A B‴ subunit |