Figure 4 .

c-KIT mRNA and protein expression in vulvar carcinomas. (A) c-KIT mRNA expression evaluated by qRT-PCR using Relative Quantification (RQ) values (shown vertical axis). Normal samples transcript expression is shown significantly higher than tumor expression (p = 0.0009); c-KIT protein expression assessed by immunohistochemistry showing stronger immunostaining in normal area (B, arrows: normal epithelium, star: stroma) than in tumor area (C, arrow: invasive squamous cell carcinoma with irregular infiltrating borders, star: stroma).