Table 3.
Multivariate survival analysis ofCDKN2Amethylation in colorectal cancer
| |
MODEL 1 |
|
MODEL 2 |
||||
|---|---|---|---|---|---|---|---|
| HR (95%CI) | P-value | HR (95%CI) | P-value | ||||
|
CDKN2A |
Negative |
1.0 |
0.0416 |
CDKN2A |
Negative |
1.0 |
0.0021 |
| |
Methylated |
1.36 (1.1-1.8) |
|
|
Methylated |
1.66 (1.2-2.3) |
|
| Age |
Baseline |
1.0 |
|
MSI |
MSS/MSI-L |
1.0 |
0.0273 |
| |
1-year |
1.04 (1.02-1.05) |
<0.0001 |
|
MSI-H |
0.63 (0.4-0.9) |
|
| pT |
pT1-2 |
1.0 |
<0.0001 |
BRAF |
Wild-type |
1.0 |
0.2165 |
| |
pT3-4 |
1.98 (1.3-2.9) |
|
|
Mutation |
1.32 (0.9-2.0) |
|
| pN |
pN0 |
1.0 |
<0.0001 |
|
|
|
|
| pN1-2 | 2.52 (1.9-3.3) | ||||||