Table 1.
Effects of Rimonabant with dietary intervention on physical and biochemical parameters over the study period (n = 20) (Mean ± SD)
| Baseline | 6 Months | |
|---|---|---|
| Weight (Kg) |
112 ± 21 |
107 ± 21*** |
| Waist circumference (cm) |
124 ± 13 |
121 ± 13** |
| Fat mass (Kg) |
44 ± 12 |
42 ± 12 |
| HbA1c (%) |
8.0 ± 1.6 |
7.4 ± 1.7* |
| Total cholesterol (mmol/L) |
4.4 ± 1.0 |
4.4 ± 1.0 |
| LDL cholesterol (mmol/L) |
2.3 ± 0.8 |
2.4 ± 0.9 |
| HDL cholesterol (mmol/L) |
1.2 ± 0.2 |
1.3 ± 0.2** |
| Triglyceride (mmol/L) |
1.9 ± 1.1 |
1.7 ± 0.9 |
| Insulin dose (units / day) |
116 ± 59 |
102 ± 71* |
| Systolic blood pressure (mmHg) |
147 ± 21 |
142 ± 24 |
| Diastolic blood pressure (mmHg) | 85 ± 8 | 83 ± 11 |
*p < 0.05 in comparison to baseline.
**p < 0.01 in comparison to baseline.
***p < 0.001 in comparison to baseline.