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. 2012 Aug 16;10:164. doi: 10.1186/1479-5876-10-164

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Copyright ©2012 Sheu et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The mRNA expressions of inflammatory and anti-inflammatory biomarkers in ischemic quadriceps by day 21 after CLI procedure (n = 8). A, B and C) indicating mRNA expressions of tumor necrotic factor (TNF-α), matrix metalloproteinase (MMP-9), and plasminogen activator inhibitor (PAI)-1, respectively.* vs. other groups with different symbols, p < 0.0004. D &E) showing mRNA expressions of interleukin (IL)-10 and endothelial nitric oxide (eNOS), respectively.* vs. other groups with different symbols, p < 0.009. Statistical analysis in each group by ANOVA followed by Bonferroni multiple comparison post hoc test. CLI = critical limb ischemia; Cil = cilostazol; Clo = clopidogrel.