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. 2012 Sep 3;5:21. doi: 10.1186/1757-2215-5-21

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Copyright ©2012 Huang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The incidence of ovarian cancer of DMBA-treated rats and representative images of the tumors formed. Tumors were detected by palpating the abdominal wall of rats once a week for a total of 32 weeks to monitor tumor progression and validated by a histological examination. Open circles, rats of the S group; closed circles, rats of the CS group (A). Tumors were usually a single invasive nodule (B, C), some were intraperitoneal spread or seeding of tumor (D), with or without ascites. Arrows refers to the tumor.