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. 2012 Jul 20;2012(1):10. doi: 10.1186/1687-4153-2012-10

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Copyright ©2012 Besozzi et al.; licensee Springer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Deterministic simulations of cAMP dynamics under deletion of Pde1 or Pde2 with different initial amounts of Cdc25. The figure shows the dynamics of cAMP with different initial amounts of Cdc25, obtained by means of deterministic simulations when deleting Pde1 (left) and Pde2 (right). In both conditions, no sustained oscillations are present in the system for any value of the initial amount of Cdc25.