Figure 2. Inhibitory effects of K-134 on infarction volume in a photothrombotic cerebral infarction model.

Preadministration of K-134 but not cilostazol significantly and reduced cerebral infarction volume in a photothrombotic cerebral infarction model in comparison with vehicle-treated controls (A). Values are means ± SEM (*P<0.05, two-tailed Dunnett's test, n = 12). (B) Representative photographs (1.35 cm×1.65 cm) show TTC-stained brain sections sliced at the location of bregma. The white-colored area represents the infarct region. Data shown are representative of two experiments with similar results.