Figure 3. Global analysis of the relationship between esimated number of rotavirus gastroenteritis deaths avoided versus intussusception deaths caused by removal of the age restrictions for rotavirus vaccination.

These estimates are from 2,000 simulations with each blue dot representing a potential estimate of rotavirus deaths prevented (y-axis) versus intussusception deaths caused (x-axis) from removal of the age restrictions given the uncertainty on the parameters in the model: rotavirus mortality, vaccine efficacy, vaccine coverage, intussusception incidence, intussusception risk from vaccine, and intussusception fatality. The black square represents the median estimate.