Table 3. Hazard Ratios for Death among Patients with HIV-infection and Culture-Confirmed Pulmonary TB Alive at Diagnosis and Initiated Therapy, United States, 1993–2006.
Population* | Died | Completed Therapy† | Adj. HazardRatio§ (95% Conf. Int.) |
HIV-infected, 1993–2006 (overall) | |||
Smear-positive | 2,212 (27) | 6,107 (73) | Referent |
Smear-negative | 1,112 (22) | 4,053 (78) | 0.81 (0.76–0.88) |
HIV-infected, 1993–1997 | |||
Smear-positive | 1,527 (33) | 3,072 (67) | Referent |
Smear-negative | 756 (27) | 2,026 (73) | 0.82 (0.75–0.90) |
HIV-infected, 1998–2006 | |||
Smear-positive | 685 (18) | 3,035 (82) | Referent |
Smear-negative | 356 (15) | 2,027 (85) | 0.81 (0.71–0.92) |
Excluding patients reported after 2006 (536 smear-positive, 431 smear-negative), not documented as alive at diagnosis (191 smear-positive, 362 smear-negative), with no documented treatment (35 smear-positive, 112 smear-negative), or whose recorded outcome date preceded start of therapy or was missing (153 smear-positive, 110 smear-negative).
Other outcomes not represented as a column in this table include patients who moved during treatment or were lost (650 smear-positive, 484 smear-negative), were uncooperative with therapy (52 smear-positive, 45 smear-negative), or whose outcomes were otherwise not known (35 smear-positive, 30 smear-negative),
Adjusted for gender, age group, race/ethnicity, nationality, incarceration, alcohol and drug use, and previous TB; after adjustment, homelessness in the previous year was the only examined covariate that was no longer statistically significant.