Table 1. Polarized localization of Laminin V is lost with Hugl knockdown.

Cell Line	LamV polarized	LamV unpolarized	n	% polarized	Fisher’s exact test
Control shRNA (MC)	51	3	54	94%
Hugl1 shRNA (MH11)	23	38	61	38%	p<0.0001
Control shRNA (MC)	40	3	43	93%
Hugl2 shRNA (MH2C)	11	26	37	30%	p<0.0001

Laminin V localization within acinar structures was scored as polarized (exclusively basal) or unpolarized (apical or luminal localization) and statistical significance was calculated using 2×2 contingency tables and Fisher’s Exact test. Data in table is reflective of one of three trials producing similar statistically significant results.