Table 1.
Demographic characteristics of the Parkinson’s disease patients with and without pathological gambling
Parkinson’s disease patients with pathological gambling (n = 7) | Parkinson’s disease patients without pathological gambling (n = 7) | P-value | |
---|---|---|---|
Gender | Five males, two females | Six males, one female | |
Age | 47–72 years | 51–74 years | 0.5 |
H & Y, mean (±SD) | 2 (±0.6) | 1.9 (±0.7) | 0.6 |
PDRS (III), mean (±SD), off medication | 25.2 (±4.5) | 20.2 (±5.4) | 0.09 |
Disease duration, mean years (±SD) | 7.4 (±3.2) | 5.6 (±2.5) | 0.15 |
Current Total LEDD, mean (±SD) | 856 (±407) mg | 756 (± 400) mg | 0.6 |
Current Dopamine agonist LEDD, mean (±SD) | 138 (±172) mg | 167 (±113) mg | 0.7 |
MoCA, mean (±SD) | 26 (±3.2) | 28 (±2.3) | 0.2 |
G-SAS, mean (±SD) | 34.8 (±5.6) | 4.6 (±6.3) | <0.001 |
H & Y = Hoehn and Yahr; UPDRS III = Unified Parkinson’s Disease Rating Scale, motor score; LEDD = levodopa equivalent daily dose: L-dopa dose + L-dopa dose × 1/3 if on entacapone + bromocriptine (mg) × 10 + cabergoline or pramipexole (mg) × 67 + ropinirole (mg) × 20 + pergolide (mg) × 100 + apomorphine (mg) × 8 (from Evans et al., 2004); MocA = Montreal Cognitive Assessment; G-SAS = Gambling Symptom Assessment Scale.