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. 2012 Aug 9;40(19):9815–9824. doi: 10.1093/nar/gks740

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Structure of Cid1–MgUTP complex. (A) Overview of Cid1–MgUTP structure. UTP binds into a cleft between the catalytic and central domains of Cid1. UTP is shown in ball and stick representation, Cid1 is shown as ribbon representation. (B) UTP molecule from Cid1–MgUTP structure with a F_o − F_c omitted map (green mesh) contoured at 3 σ. (C) Cid1 recognition of Mg²⁺ and triphosphate moieties of UTP. Mg²⁺shown as sphere. (D) Key ribose/base interactions between Cid1 and UTP.