Table 2.

Two dimensional cadherin affinities and dissociation rates from cell binding kinetics

Cadherin on Test Cell	Density(#/μm2)§	Cadherin- Fc on Red Cell	Density(#/μm2)¶	2D Affinity(× 10−4 μm2)	Dissociation rate (s−1)	Ref.
C-cadherin	18	C-cadherin	10	11 ± 2	0.6 ± 0.2	[7]
C-cadherin	7	C-EC1245	10	30 ± 9	0.3 ± 0.1
C-cadherin	7	C-EC12	155	1.4 ± 0.5	0.9 ± 0.2
C-cadherin W2A	24	C-cadherin	452	0.12±0.05	0.10 ± 0.03
N-cadherin	15	N-cadherin	69	1.9 ± 0.3	1.1 ± 0.4	[10]
E-cadherin	16	E-cadherin	44	3.3 ± 0.5	1.0 ± 0.3	[9]
C-cadherin	14	N-cadherin	38	3.5 ± 0.2	1.3 ± 0.3	[10]
C-cadherin	18	E-cadherin	33	3.3 ± 0.9	1.3 ± 0.4	[9]
N-cadherin	16	E-cadherin	33	2.6 ± 0.4	1.2 ± 0.5

^§Density (#/square micron) of full-length cadherin on the Chinese hamster ovary cell and

^¶Density (#/square micron) of Fc-tagged cadherin immobilized and oriented on the apposing red blood cell.