Table 3.
Effects of SRFE on ADH and ALDH levels in acutely inebriated rats.
| Groups | Doses (g/kg) | Ethanol (g/kg) | Stomach | Small intestine | Liver | |||
|---|---|---|---|---|---|---|---|---|
| ADH (U/g prot) |
ALDH (μmol/L) |
ADH (U/g prot) |
ALDH (μmol/L) |
ADH (U/g prot) |
ALDH (μmol/L) |
|||
| Control | — | 0.00 | 0.95 ± 0.03 | 0.39 ± 0.01 | 2.75 ± 0.20 | 1.65 ± 0.06 | 7.56 ± 0.33 | 6.31 ± 0.08 |
| SRFE control | 0.16 | 0.00 | 1.10 ± 0.05# | 0.42 ± 0.01 | 3.12 ± 0.14 | 1.73 ± 0.11 | 9.56 ± 0.34## | 8.10 ± 0.10## |
| Model | — | 4.50 | 0.85 ± 0.07 | 0.36 ± 0.02# | 2.49 ± 0.26 | 0.46 ± 0.08## | 8.87 ± 0.57 | 7.92 ± 0.33## |
| SRFE | 0.04 | 4.50 | 0.97 ± 0.05 | 0.38 ± 0.01 | 2.75 ± 0.27 | 0.45 ± 0.05 | 8.92 ± 0.45 | 7.91 ± 0.21 |
| 0.08 | 4.50 | 0.97 ± 0.05 | 0.41± 0.02∗ | 2.91 ± 0.22 | 0.57 ± 0.10 | 9.29 ± 0.53 | 8.11 ± 0.28 | |
| 0.16 | 4.50 | 1.07± 0.05∗ | 0.41± 0.01∗ | 3.27 ± 0.22∗ | 1.19 ± 0.14∗∗ | 9.77 ± 0.35 | 8.27 ± 0.26 | |
| HWJZ | 0.25 | 4.50 | 0.97 ± 0.06 | 0.36 ± 0.01 | 2.81 ± 0.22 | 0.80 ± 0.14 | 10.47 ± 0.50∗ | 9.95 ± 0.24∗∗ |
SRFE: Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae extract; HWJZ: Hai-Wang-Jin-Zun tablet; ADH: ethanol dehydrogenase; ALDH: acetaldehyde dehydrogenase. Means ± S.E.M., n = 9. # P < 0.05, ## P < 0.01 versus control; *P < 0.05, **P < 0.01 versus model.