Table 4. The various published single-institution reports of outcomes and toxicity using intensity-modulated radiotherapy for total mucosal irradiation in squamous cell carcinoma with unknown primary.
| Author | Patients, n | RT alone | Surgery and RT | Chemoradiation therapy | LRC (2 years) | OS (2 years) | Acute Grade 3 mucositis |
| Klem [64] | 21 | 5 | 16 | 14 | 85% | 85% | 14% |
| Madani [66] | 23 | 4 | 19 | 3 | NR | 75% | 50% |
| Lu [65] | 18 | 6 | 12 | 6 | 88% | 74% | NR |
LRC, locoregional control rate; NR, not reported; OS, overall survival; RT, radiotherapy.