Table 6.
Diagnostic usefulness of the assayed parameters for the occurrence of ACS.
| Variable | Cut-off value | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
|---|---|---|---|---|---|
| CRP (mg/L) |
0.85* | 0.84 | 0.62 | 86% | 58% |
| 3.00# | 0.48 | 0.89 | 90% | 46% | |
| TC : HDL-C | 3.72 | 0.77 | 0.79 | 88% | 63% |
| LDL-C : HDL-C | 2.15 | 0.76 | 0.70 | 84% | 59% |
| TG : HDL-C | 1.55 | 0.85 | 0.59 | 81% | 66% |
| apoB : apoA-I | 0.53 | 0.74 | 0.56 | 77% | 51% |
*The optimal cut-off value for hsCRP test determined by ROC analysis in our study.
#A lower limit for the high risk category according the CDC and AHA statement on markers of inflammation and cardiovascular disease [6].
ACS: acute coronary syndrome; AHA: the American Heart Association; apoB : apoA-I: apolipoprotein B to apolipoprotein A-I ratio; CDC: the Centers for Disease Control and Prevention; CRP: C-reactive protein; LDL-C : HDL-C: low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio; TC : HDL-C: total cholesterol to high-density lipoprotein cholesterol ratio; TG : HDL-C: triglycerides to high-density lipoprotein cholesterol ratio.