TABLE I.
Characteristics of participants who received single-photon emission-computed tomography (SPECT) of the brain for sixty (60) minutes, twenty-four (24) hours following the intravenous injection of approximately 333 MBq (9 mCi) (−)-5-[123I]iodobenzovesamicol ([123I]IBVM)
| Diagnosis | Age in years | Sex | Ethnicity | Arterial blood sampling | [123I]IBVM in MBq (mCi) | VATSBI |
|---|---|---|---|---|---|---|
| Healthy | 19 | M | C | 1 | approximately 333 (9.00) | 8.14 |
| Healthy | 21 | M | C | 1 | 344.1 (9.30) | 5.88 |
| Healthy | 27 | F | A | 1 | 268.99 (7.27) | 6.47 |
| Healthy | 28 | M | A | 1 | 334.11 (9.03) | 3.66 |
| Healthy | 31 | F | AA | 0 | 280.83 (7.59) | 5.30 |
| Healthy | 32 | F | AA | 0 | 333 (9.00) | 3.34 |
| Healthy | 33 | F | AA | 0 | approximately 333 (9.00) | 5.88 |
| Healthy | 34 | F | C | 1 | approximately 333 (9.00) | 6.96 |
| Healthy | 44 | F | AA | 1 | 340.4 (9.20) | missinga |
| Rett syndrome | 19 | F | AA | 0 | 321.9 (8.70) | 4.26 |
| Rett syndrome | 21 | F | C | 0 | approximately 333 (9.00) | 6.34 |
| Rett syndrome | 22 | F | C | 0 | approximately 333 (9.00) | 4.82 |
| Rett syndrome | 31 | F | C | 0 | 257.15 (6.95) | 5.34 |
0 = no, 1 = yes; A = Asian; AA = African-American; C = Caucasian; F = female; M = male; VATSBI = Vesicular Acetylcholine Transporter Binding Site Index.
a
Meaningful data was not obtained due to technical malfunction of the gamma counter.