Table II.
Rate constants of reversibly binding radioligands estimated by mathematical modeling for healthy control participants who received intravenous injections of approximately 333 MBq (9 mCi) (−)-5-[123I]iodobenzovesamicol ([123I]IBVM)
Age in years | Striatal K1 | Striatal k2 | Striatal k3 | Cerebellar K1 | Cerebellar k2 | Cerebellar k3 |
---|---|---|---|---|---|---|
19 | 0.0196 | 0.0137 | 0.0062 | 0.0205 | 0.0489 | 0.0038 |
21 | 0.0233 | 0.0158 | 0.0176 | 0.0249 | 0.0348 | 0.0065 |
27 | 0.00097 | 0.0099 | 0.012 | 0.0011 | 0.037 | 0.006 |
28 | 0.0122 | 0.0174 | 0.0225 | 0.0121 | 0.0312 | 0.0064 |
34 | a | a | a | a | a | a |
44 | a | a | a | a | a | a |
Technical problems prevented meaningful estimates of the constants.