Table 5.
Pearson Correlation Coefficients Between Compounds 1.1 and 1.21 and other known Actin-Binding Natural Products. Correlations were obtained for the GI50 level of response.
| Name | NSC | GI50 to 1.1 | GI50 to 1.21 |
|---|---|---|---|
| aplyronine A | 687160 | −0.11 | −0.03 |
| cytochalasin A | 174119 | 0.55 | 0.42 |
| cytochalasin B | 107658 | 0.55 | 0.49 |
| cytochalasin D | 209835 | 0.71 | 0.63 |
| cytochalasin E | 175151 | 0.71 | 0.66 |
| cytochalasin H | 305222 | 0.69 | 0.56 |
| cytochalasin Q | 675858 | 0.69 | 0.49 |
| dolastatin 11 | 606195 | 0.37 | 0.45 |
| jasplakinolide | 613009 | 0.34 | 0.41 |
| latrunculin A | 613011 | 0.58 | 0.44 |
| mycalolide C,D mixture | V4827 | 0.28 | 0.50 |
| mycalolide E | V4828 | 0.30 | 0.50 |
| swinholide H | 685570 | 0.49 | 0.61 |