Figure 9.

Typical experiment showing a mouse colon treated with (A) peanut agglutinin-conjugated and (B) anticarcinoembryonic antigen antibody-conjugated iron oxide-human serum albumin near-infrared fluorescent nanoparticles. Each set of experiments includes a color photograph, a fluorescent image, and a logarithmically scaled fluorescent image. (C) Untreated tumor indicating a negligible level of tumor autofluorescence. (B and C) Bioactive, conjugated fluorescent iron oxide-human serum albumin nanoparticles selectively label the LS174T tumors and leave the surrounding nonpathological tissue relatively unlabeled, with a signal-to-background ratio of 1 : 1 × e²⁵.

Note: This experiment was repeated three more times with similar results.