Table 4.
Univariate Analysis |
Multivariate Analysis |
|||||
---|---|---|---|---|---|---|
HR | 95% CI | P (2–sided Wald test) | HR | 95% CI | P (2–sided Wald test) | |
1q gain (FISH) | 0.554 | 0.202 | ||||
Yes vs no | 1.4 | (0.5, 4.4) | 2.0 | (0.7, 5.8) | ||
Nucleolin (IHC, % positive cells) | 0.130 | 0.539 | ||||
>50% vs ≤50% | 2.1 | (0.8, 5.6) | 1.3 | (0.6, 2.6) | ||
EGFR (IHC) | 0.340 | 0.714 | ||||
Low vs strong | 1.7 | (0.6, 5.2) | 1.2 | (0.5, 2.5) | ||
EGFR (mRNA)* | 0.328 | 0.377 | ||||
10.1 vs 5.1 | 1.6 | (0.9, 2.8) | 1.4 | (0.8, 2.4) | ||
32.7 vs 5.1 | 3.2 | (0.7, 14.6) | 2.6 | (0.7, 9.8) | ||
PROM1 (mRNA)* | 0.993 | 0.967 | ||||
53.5 vs 26.8 | 1.0 | (0.5, 1.9) | 0.9 | (0.5, 1.9) | ||
80.9 vs 26.8 | 1.0 | (0.4, 2.3) | 0.9 | (0.4, 2.2) | ||
HTERT (mRNA)* | 0.024 | 0.011 | ||||
6.2 vs 1.2 | 1.5 | (1.1, 2.1) | 1.7 | (1.2, 2.3) | ||
33.5 vs 1.2 | 7.1 | (1.7, 29.2) | 9.9 | (2.2, 44.3) |
*The 3 values are the quartiles of the variable distribution.