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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Int J Cancer. 2011 Aug 25;131(1):30–40. doi: 10.1002/ijc.26323

Fig. 2.

Fig. 2

Regulation of caspase-3/7 activity, apoptosis and apoptosis-related proteins by EGCG on CSCs derived from human primary pancreatic tumors. (A), Regulation of caspase-3/7 activity by EGCG. CSCs were treated with EGCG (0-60 μM) for 24 h, and caspase-3/7 activity was measured as per manufacturer’s instructions. Data represent mean ± SD. *, # or % = significantly different from control, P < 0.05. (B), Regulation of apoptosis by EGCG. CSCs were treated with EGCG (0-60 μM) for 48 h, and apoptosis was measured by TUNEL assay. Data represent mean ± SD. *, # or % = significantly different from control, P < 0.05. (C), Regulation of apoptosis-related proteins. Pancreatic CSCs were treated with EGCG (0-60 μM) for 36 h. Real time PCR (q-RT-PCR) was performed to examine the expression of Bcl-2, survivin, XIAP, and GAPDH. Data represent mean ± SD. *, # or % = significantly different from control, P < 0.05.