Table 3.

Genes regulated by both low dose and high dose risedronate with 24 hr treatment.

		10−8M		10−4M
Symbol	Description	Fold	P value	Fold	P value
	Signaling Array
Hk2	Hexokinase 2	10.1	0.003	2.3	0.02
Fos	FBJ murine osteosarcoma viral oncogene homolog	10.1	0.003	12.3	0.002
Fas	Fas (TNF receptor superfamily, member 6)	2.9	0.003	2.5	0.004
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	2.4	0.0003	3.1	0.0002
Pparg	Peroxisome proliferator activated receptor gamma	2.1	0.006	5.4	0.001
Birc1b	Baculoviral IAP repeat-containing 1b	0.4	0.009	0.2	0.003
	Osteogenesis Array
Mmp8	Matrix metallopeptidase 8	5.4	0.02	6.5	0.02
Mmp10	Matrix metallopeptidase 10	2.9	0.02	5.2	0.008
Col7a1	Procollagen, type VII, alpha 1 (predicted)	0.4	0.00007	0.3	0.00003
Col6a1	Procollagen, type VI, alpha 1 (predicted)	0.4	0.0008	0.4	0.0009
Tfip11	Tuftelin interacting protein 11	0.3	0.0005	0.5	0.001
Comp	Cartilage oligomeric matrix protein	0.2	0.00002	0.1	0.00001
Flt1	FMS-like tyrosine kinase 1, VEGFR1	0.08	0.001	0.09	0.002
Bmpr1a	Bone morphogenetic protein receptor, type 1A	0.04	0.006	0.05	0.006