Table 1. Characteristics of Rotarix and RotaTeq vaccines for the prevention of rotavirus associated diarrhoea.
Rotarix | Source | RotaTeq | Source | |
Manufacture | Glaxo Smith Kline | [11] | Merck | [12] |
Doses | 2 doses | [11] | 3 doses | [12] |
Vaccine virus | G1P(8) | [11] | G1,G2,G3,G4,P1A(8) | [12] |
Concentration | 106 CCID | [11] | 2.2×106 G1, 2.8×106 G2, 2.2×106 G3, 2.0×106 G4, 2.3×106 P1A(8) | [12] |
Cross potection | G1, G3, G4, G9 | [11] | G1,G2,G3,G4 | [12] |
Administration | Oral | [11] | Oral | [12] |
Timing of doses | 6–24 weeks | [11] | 6–32 weeks | [12] |
Interval between doses | Minimal 4 weeks | [11] | 4 to 10 weeks | [12] |
Store temp vial | 2–8 degrees celcius | [11] | 2–8 degrees celcius | [12] |
Use within | 24 hours | [12] | As soon as possible | [12] |
Package size vial | 17.1cm3 per dose (full course: 34.2cm3) | [38] | 46.3cm3 per dose (full course: 138.9cm3) | [38] |
Vaccine Vial Monitor technology | Yes | [38] | No | [38] |
Price | $2.5 per dose, $5 full course | [25] | $3.5 per dose, $10.5 full course | [26] |
Shelf life | 24 months | [11] | 24 months | [12] |
Adverse events | Low | [11] | Low | [12] |
Thermostability | Proven | [37] | Unproven |