| Male |
3,412 |
13,648 |
2,084 |
8,336 |
5,496 |
21,984 |
| Female |
1,814 |
7,256 |
1,326 |
5,304 |
3,140 |
12,560 |
| Total (male and female) |
5,226 |
20,904 |
3,410 |
13,640 |
8,636 |
34,544 |
| Mean Age (at time of diagnosis of case) |
63·4 |
63·4 |
66.5 |
66.5 |
64·7 |
64·7 |
| Mean age men |
61·6 |
61·6 |
65.6 |
65.6 |
63·1 |
63·1 |
| Mean age women |
67·0 |
67·0 |
68.1 |
68.1 |
67·5 |
67·5 |
| Mean years observed in data base |
6·3 |
6·3 |
5.7 |
5.7 |
6·1 |
6·1 |
| Smoking-any positive record of smoking (%) |
2,229 (51.5) |
8,437 (45.4) |
1,303 (46.5) |
5,274 (43.9) |
3,532 (49.5) |
13,711 (44.9) |
| Dyspepsia–any record up to 12 mths before cancer diagnosis in cases and equivalent date in controls (%) |
1,169 (22.3) |
4,184 (20.0) |
827 (24.3) |
2,910 (21.3) |
1,996 (23.1) |
7,094 (20.5) |
| PPI-any use within study window (%) |
1,100 (21.1) |
3,215 (15.4) |
728 (21.4) |
2,073 (15.2) |
1,828 (21.2) |
5,288 (15.3) |
|
H. pylori positive–any record |
121 (2.3) |
491 (2.4) |
128 (3.8) |
321 (2.4) |
249 (2.9) |
812 (2.4) |
| BMI>30 (%) |
88 (1.7) |
1,621 (7.8) |
58 (1.8) |
948 (6.7) |
146 (1.7) |
2,569 (7.44) |
| Alcohol intake–any record greater than recommended limits (%) |
620 (11.9) |
2,293 (11.0) |
286 (8.4) |
1,345 (9.9) |
906 (10.5) |
3,638 (10.5) |
| Prescribed bisphosphonate-male and female (%) |
225 (4·3) |
749 (3·6) |
117 (3.4) |
478 (3.5) |
342 (4·0) |
1227 (3·6) |
| Men (%) |
54 (1.6) |
246 (1.8) |
24 (1.2) |
124 (1.5) |
78 (1.4) |
370 (1.7) |
| Women (%) |
171 (7.8) |
503 (6.9) |
93 (7.0) |
354 (6.7) |
264 (8.4) |
857 (6.8) |
| Prescribed alendronate (%) |
119 (2·3) |
410 (2·0) |
72 (2.1) |
252 (1.9) |
191 (2·2) |
662 (1·9) |
| Men (%) |
24 (0.7) |
122 (0.9) |
14 (0.7) |
68 (0.8) |
38 (0.7) |
190 (0.9) |
| Women (%) |
95 (5.2) |
288 (4.0) |
58 (4.4) |
184 (3.5) |
153 (4.9) |
472 (3.8) |
| Prescribed bisphosphonate–xcluding those used to treat metastases (%) |
218 (4·2) |
726 (3·5) |
113 (3.3) |
461 (3.4) |
331 (3·8) |
1,187 (3·5) |
| Prescribed bisphosphonates-less than 10 prescriptions-mean number per time observed in database |
3·8 |
4·0 |
3.9 |
3.8 |
3·8 |
3·9 |
| Prescribed bisphosphonates–more than 10 prescriptions–mean number per time observed in database |
26·5 |
26·2 |
23.0 |
26.0 |
25·4 |
26·1 |
