Table 1. Frequency of positivity and parasite density by LDU index values in the liver and spleen of hamsters experimentally inoculated with PP75 or Wild L. infantum strains.
| Strain/months after infection | |||||||||
| Groups | PP75 | Wild | |||||||
| 1 | 3 | 6 | 9 | 1 | 3 | 6 | 9 | ||
| ID | |||||||||
| Liver | – | – | – | – | – | – | – | – | |
| Spleen | – | – | – | – | – | – | – | – | |
| IP | |||||||||
| Liver | – | – | – | – | – | – | 6/10 (60%) | 7/8 (87%) | |
| 238.2±48a | 220.2±337 a | ||||||||
| Spleen | – | – | – | – | – | 2/10 (20%) | 9/10 (90%) | 8/8 (100%) | |
| 0.43±0.08 | 6.08±11.08a | 147±399a | |||||||
| IC | |||||||||
| Liver | – | – | 4/10 (40%) | 4/9 (44%) | 8/10 (80%) | 9/10 (90%) | 10/10 (100%) | 6/6 (100%) | |
| 34.4±42.7a,b | 218.2±281.1a,b | 58.81±59.81a,b | 168.8±163.5a,b | 1325±1312a | 3425±2634a,b | ||||
| Spleen | – | – | 4/10 (40%) | 7/10 (70%) | 7/10 (70%) | 10/10 (100%) | 10/10 (100%) | 6/6 (100%) | |
| 12.13±10.3a,b | 456.7±103a,b | 1.61±1.13a,b | 5.75±4.48a,b | 827±928a,b | 2381±19.01a,b | ||||
Significant differences (p<0.05) between infection with the different routes of inoculation are represented by “a” and “b” related to the ID and IP groups, respectively.
ID = intradermal route; IP = intraperitoneal route; IC = intracardiac route.